Dr. Boris A. Feniouk

Associate Dean for Research
School of Bioengineering and Bioinformatics
Moscow State University
Leninskiye Gory, 1-73
Moscow, 119991
Russia

Tel: +7 (495) 939-59-45
Fax: +7 (495) 939-41-95
E-mail: feniouk@fbb.msu.ru

Publications List



Education:

1990 - 1995
 Bioorganic chemistry dept., School of biology, Moscow State University.
Magister degree in biochemistry, diploma with honors.
1995-1998
 Photobiochemistry dept., A.N.Belozersky Institute of Physico-Chemical
Biology, Moscow State University. Post-graduate student, PhD project.
1999
 PhD degree. Thesis title: Investigation of proton transport and ATP synthesis
coupling mechanism of ATP synthase from purple bacterium Rhodobacter capsulatus.


Experience

1996
 A.N.Belozersky Institute of Physico-Chemical Biology, Moscow State University. Joint Russian-German project on investigating the role of chloride in bioenergetics of alkalophyllic halophyllic bacteria. Supervisor - Prof. V. P. Skulachev. Supported by INTAS grant N 93-742-Extension.
1997-2002
 Division of Biophysics, Dept. of Biology,  University of Osnabrück (Germany) in collaboration with Dept. of Bioenergetics, A.N.Belozersky Institute of Physico-Chemical Biology, Moscow State University.
Joint Russian-German project on proteins involved in transmembrane proton translocation supported by Deutsche Forschungsgemeinschaft grant DFG-RUS-436 . Supervisors: Prof. W. Junge and Dr. A. Mulkidjanian.
2000
 Short-term EMBO Fellowship, Laboratory of Molecular Biophysics, Oxford University (UK). Molecular dynamics simulations of  Na+-ATP synthase c-subunit. Supervisor - Prof. M.S.P. Sansom.
2001
 Short visit to the group of Prof. B.A. Melandri, Dept. of Biology, University of Bologna (Italy). Introduction of single aminoacid mutations in ATP synthase of Rhodobacter capsulatus.
2003-2005
 Alexander von Humboldt Research Fellow at the Division of Biophysics, Dept. of Biology,  University of Osnabrück (Germany). Project on the investigation of ATP synthase coupling mechanism.
2005-2007
 Postdoc, ATP Systems Project, Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST) at Tokyo Institute of Technology (Japan). Investigation of subunit epsilon regulatory role in Bacillus PS3 ATP synthase.
2007-2008
 Postdoc at Chemical Resources Lab, Tokyo Institute of Technology (Japan). Investigaiton of the regulatory mechanisms in Bacillus PS3 ATP synthase.
2009-2010
 Postdoc, Japan Science and Technology Agency (JST) ICORP ATP Synthesis Regulation Project (Japan). Investigation of MgADP-inhibition in bacterial ATP synthase.
2011-now
 Associate professor, School of Bioengineering and Bioinformatics, Lomonosov Moscow State University (Russia).


List of  Publications

1. Suzuki T, Wakabayashi C, Tanaka K, Feniouk BA, Yoshida M. (2011): Modulation of Nucleotide Specificity of Thermophilic FOF1-ATP Synthase by epsilon-Subunit.
J Biol Chem. 286, pp.16807-16813.

2. Saita E, Iino R, Suzuki T, Feniouk BA, Kinosita K Jr, Yoshida M. (2010): Activation and stiffness of the inhibited states of F1-ATPase probed by single-molecule manipulation.
J Biol Chem. 285, pp.11411-11417.

3. Feniouk BA, Kato-Yamada Y, Yoshida M, Suzuki T. (2010): Conformational transitions of subunit epsilon in ATP synthase from thermophilic Bacillus PS3.
Biophys J. 98, pp.434-442.

4. Feniouk, B.A., and Junge, W. (2009): Proton translocation and ATP synthesis by the F0F1-ATPase of purple bacteria.
In: The Purple Phototrophic Bacteria C. Hunter, N., Daldal, F., Thurnauer, M.C., and Beatty, J.T. (eds). Dordrecht: Springer, pp.475–493.

5. Feniouk B.A., and Yoshida M. (2008): Regulatory Mechanisms of Proton-Translocating FOF1-ATP Synthase.
Results Probl. Cell. Differ. 45, pp.279-308.

6. Suzuki T., Ozaki Y., Sone N., Feniouk B.A., and Yoshida M. (2007): The product of uncI gene in F1FO-ATP synthase operon plays a chaperone-like role to assist c-ring assembly.
Proc Natl Acad Sci U S A. 104, pp.20776-20781.

7. Feniouk B.A., Rebecchi A., Giovannini D., Anefors S., Mulkidjanian A.Y., Junge W., Turina P., Melandri B.A. (2007): Met23Lys mutation in subunit gamma of FOF1-ATP synthase from Rhodobacter capsulatus impairs the activation of ATP hydrolysis by protonmotive force.
Biophys. et Biochim. Acta, 1767, pp.1319-1330.

8. Feniouk B.A., Suzuki T., and Yoshida M. (2007): Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase.
J. Biol. Chem., 282, pp.764-772.

9. Feniouk B.A., Suzuki T., and Yoshida M. (2006): The role of subunit epsilon in the catalysis and regulation of FOF1-ATP synthase.
Biophys. et Biochim. Acta, 1757, pp.326-338.

10. Feniouk BA, Junge W. (2005): Regulation of the F0F1-ATP synthase: the conformation of subunit epsilon might be determined by directionality of subunit gamma rotation.
FEBS Lett. 579, pp.5114-5118

11. B. A. Feniouk, A. Y. Mulkidjanian, and W. Junge. (2005): Proton slip in the ATP synthase of Rhodobacter capsulatus: induction, proton conduction and nucleotide dependence.
Biophys. et Biochim. Acta, 1706, pp. 184-194

12. B. A. Feniouk, M. A. Kozlova, D. A. Knorre, D. A. Cherepanov, A. Y. Mulkidjanian, and W. Junge. (2004): The proton driven rotor of ATP synthase: Ohmic conductance (10 fS), and absence of voltage gating.
Biophys. J. 86, pp.4094-4109

13. D.A. Cherepanov, B.A. Feniouk, W. Junge, A.Y. Mulkidjanian.  (2003) Low dielectric permittivity of water at the membrane interface: effect on the energy coupling mechanism in biological membranes.
Biophys. J. 85, pp. 1307-16.

14. B. A. Feniouk, D. Cherepanov, Voskoboinikova N.E., A. Y. Mulkidjanian, and W. Junge. (2002): Chromatophore Vesicles of Rhodobacter capsulatus Contain on Average One FOF1-ATP Synthase Each.
Biophys. J. 82, pp.1115-22.

15. Boris A. Feniouk, Dmitry A. Cherepanov, Wolfgang Junge and Armen Y. Mulkidjanian (2001): Coupling of proton flow to ATP synthesis in Rhodobacter capsulatus: F0F1-ATP synthase is absent from about half of chromatophores.
Biophys. et Biochim. Acta, 1506, pp.189-203.

16. Feniouk, B. A., Cherepanov, D. A., Junge, W., Mulkidjanian, A. Y. (1999): ATP synthase of Rhodobacter capsulatus: coupling of proton flow through FO to reactions in F1 under the ATP synthesis and slip conditions.
FEBS Lett. 445, pp.409-14.

17. Feniouk, B. A., Junge, W., Mulkidjanian, A. Y. (1998): ATP-synthase of Rhodobacter capsulatus: proton flow and ATP synthesis in response to light flashes.
In: Photosynthesis: Mechanisms and Effects, Ed. G. Garab (Kluver Academic Publishers, Dordrecht), pp.1679-1682.

18. Gopta O. A., Feniouk B. A., Junge W., Mulkidjanian A. Y. (1998): The cytochrome bc1 complex of Rhodobacter capsulatus: ubiquinol oxidation in a dimeric Q-cycle?
FEBS Lett. 431, pp.291-296

19. Avetisyan, A.V., Kaulen, A.D., Skulachev, V.P., Feniouk, B.A. (1998): Photophosphorylation in alkalophilic halobacterial cells containing halorhodopsin: chloride-Ion cycle?
Biochemistry (Mosc) 63, pp.625-628